Size-Tunable DNA-Based Micelles for Deep Tumor Penetration
نویسندگان
چکیده
منابع مشابه
Multistage nanoparticle delivery system for deep penetration into tumor tissue.
Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced permeation and retention (EPR) effect, have provided only modest survival benefits. This suboptimal outcome is likely due to physiological barriers that hinder delivery of the nanotherapeutics throughout the tumor. Many of these n...
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ژورنال
عنوان ژورنال: Chem
سال: 2019
ISSN: 2451-9294
DOI: 10.1016/j.chempr.2019.06.002